Drugs Like Lemtrada May Benefit MS Patients Right From The Start
An Italian study indicates Lemtrada may be more effective than other drugs if treatments begin early.
Tuesday, September 29, 2020 - About three million people are living with multiple sclerosis today. Most cases of multiple sclerosis begin around the age of 30. There are approximately 30,000 cases of MS in people under 18 years old worldwide. The disease progresses from mild to severe over time. There is currently no drug on the market to stop it. MS is not a fatal disease, but one that eventually can lead to permanent disability due to muscle spasticity. Those with multiple sclerosis say that it is a disease that one dies with, not dies from. Lemtrada is considered the drug of last resort for treating those with the advanced stages of the disease. Lemtrada treatments are to be considered only when all others have failed.
Lemtrada intravenous infusion is given to patients in two treatments, one for five days, and the other for three days, one year apart. Lemtrada toxicity includes a warning that people have experienced sudden death and permanent paralysis from having a heart attack or stroke during or shortly after a Lemtrada infusion. The US Food and Drug Administration requires that both Lemtrada patients and their doctors complete and sign a questionnaire attesting that they understand: "serious cases of stroke and tears in the lining of arteries in the head and neck have occurred in patients with multiple sclerosis (MS) shortly after they received Lemtrada (alemtuzumab). These problems can lead to permanent disability and even death."
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In the past, patients with RRMS and their doctors put off more intense and potentially hazardous treatments with drugs like Lemtrada, preferring to treat the disease with milder disease-modifying therapy (DMT) drugs initially. New studies indicate, however, that taking a step-by-step approach to taking ever more potent drugs as the disease progresses may not be the best course of action for some patients. Multiple Sclerosis News Today writes, "Early use of high efficacy disease-modifying therapies (DMTs) is more effective than the traditional approach - that of an escalating treatment regimen - at delaying disability progression in people with relapsing-remitting multiple sclerosis (RRMS), a real-life study from Italy reports. People later moving to more aggressive treatment also appeared to benefit less from it than those treated intensively from the start, its researchers said." Multiple Sclerosis doctors today are divided as to how aggressively to treat the disease given the profound safety profiles of more effective medicines like Truvada. Truvada carries the most severe FDA black box warning stating that the drug itself could be much more deadly than the disease it is intended to treat. In addition to instant death and paralysis, the Lemtrada homepage highlights such serious side effects as autoimmune difficulties where the cells that make up the immune system attack themselves and also may attack vital organs in the body. Blood clotting issues have been reported also, "a condition of reduced platelet counts in your blood that can cause severe bleeding that may cause life‑threatening problems."
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- Lemtrada Can Cause Sudden Death And Many Other Health Issues | 3/8/2021
- Lemtrada May Slow the Progression of Relapse Remitting MS But with Potentially Severe Side Effects | 3/5/2021
- MS Doctors May Need To Be Reminded of Lemtrada's Deadly Side Effects | 3/1/2021
- Doctors Treating RRMS Must Discuss Lemtrada's Deadly Side Effects With Patients | 2/23/2021
- Lemtrada Can Cause An Arterial Dissection and Instant Death | 1/20/2021
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- People As Young As 20 Should Watch For Symptoms of Multiple Sclerosis | 12/30/2020
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- Multiple Sclerosis Patients Suffer Fatigue Before Symptoms Gradually Increase | 9/23/2020
- Doctors May Have Dropped Lemtrada Over Covid-19 Fears | 9/2/2020
- Relapse Remitting Multiple Sclerosis Patients May Have a Promising New Drug | 8/25/2020
- Ofatumumab Could Replace Lemtrada For Treatment of Multiple Sclerosis | 8/8/2020
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- The Risks Of Lemtrada Therapy And Other DMTs | 7/9/2020
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- A Multiple Sclerosis Doctor Explains The Ins and Outs of Lemtrada for RRMS Patients in a Series of YouTube Videos | 6/22/2020
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- Canadians Have One of the World's Highest Rates of Multiple Sclerosis | 5/28/2020
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- Relapse Remitting Multiple Sclerosis Patients Share Their Lemtrada Experiences Online | 5/12/2020
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- Sanofi Forced To Pay $11.8 Million In Alleged Kick-Back Scheme | 3/16/2020
- Newly Diagnosed RRMS Patients Should Avoid Lemtrada and Look to Other Less Toxic Treatments | 3/11/2020
- Lemtrada Deaths Prompt Greater Scrutiny and Harsher Warnings | 2/27/2020
- Lemtrada Patients Dying At An Alarming Rate | 2/10/2020
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- Lemtrada Fears May Be Overdone | 1/30/2020
- Some Patients Rave About Lemtrada's Effectiveness While Others Are Left Permanently Disabled | 1/8/2020
- One Last Lemtrada Warning for 2019 | 1/2/2020
- RRMS Patients May Try Stem Cell Therapy if Lemtrada Fails | 12/26/2019
- Lemtrada Patient's Fear of the Unknown Moderated in YouTube Testimonial Videos | 12/16/2019
- Lemtrada Side Effect Awareness Requirements | 12/11/2019
- Lemtrada is serious medication for a serious condition | 11/21/2019
- More Restrictions Placed on Multiple Sclerosis Sufferers Who Wish to Receive Lemtrada Treatment | 11/15/2019
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- Europe's Medicine Agency Increases Lemtrada Restrictions | 11/4/2019
- Understand The Pros and Cons of Lemtrada RRMS Treatments | 10/16/2019
- Lemtrada Is More Deadly Than Originally Thought | 10/10/2019
- Obesity Can Make Multiple Sclerosis Medications Less Effective | 10/2/2019
- RRMS Patients Should Consider Lemtrada's Risk of Arterial Dissection | 9/18/2019
- Multiple Sclerosis Patient Have a Difficult Decision To Make When The Disease is in its Latter Stages | 9/6/2019
- Lemtrada's Deadly Side Effects Greater Than Previously Thought | 9/2/2019
- Drug Makers Look to Mitigate Lemtrada's Life-Threatening Side Effects | 8/26/2019
- Lemtrada Relieves RRMS Symptoms Allowing Patients to Enjoy a Better Quality of Life | 8/20/2019
- Lemtrada Causes High Blood Pressure Before a Stroke Occurs | 8/6/2019
- Lemtrada Patients Report Promising Results | 8/1/2019
- The European Medicines Agency is Studying Lemtrada's Side Effects | 7/30/2019
- What To Watch For Indicating You May Have Multiple Sclerosis | 7/10/2019
- Lemtrada May Be Twice as Effective As Its Leading Competitor | 7/5/2019
- Brain Bleeding May Indicate a Lemtrada Stroke is Imminent | 6/27/2019
- Treating Multiple Sclerosis From Many Angles | 6/21/2019
- Lemtrada's Risks Exceed The Black Box Warning | 6/18/2019
- A Long-Term Study Demonstrates Lemtrada's Effectiveness and Adverse Side Effects | 6/11/2019
- A Leading Authority Finds Lemtrada Causes Brain Bleeding | 5/30/2019
- Lemtrada's Incredibly Long List of Adverse Side Effects | 5/23/2019
- The Outlook is Grim For Relapsing-Remitting Multiple Sclerosis (RRMS) Patients | 5/15/2019
- Lemtrada Forced To Update Black Box Warning To Include Chance of Stroke | 5/10/2019
- The European Medicines Agency Urges Doctors To Stop Using Lemtrada Effective Immediately | 5/4/2019
- The Pros and Cons of Lemtrada Therapy | 4/19/2019
- Europe's FDA is Reviewing Lemtrada's Stroke Side Effect | 4/15/2019
- Lemtrada is a drug that is approved for patients suffering from relapsing multiple sclerosis but can have serious and often deadly side effects. | 4/9/2019
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No-Cost, No-Obligation Lemtrada Lawsuit Case Review If You or a Loved One Suffered from Lemtrada Stroke Complications
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