MS Doctors Must Weigh The Benefits of Lemtrada Versus The Drug's Stroke Risks

Lemtrada can cause MS patients expecting relief from their seizures to experience a life-threatening stroke instead

Wednesday, April 3, 2019 - According to the National Multiple Sclerosis Society, multiple sclerosis is an unpredictable condition that affects over 2 million men and women between the ages of 20 and 50 disrupting the central nervous system. Multiple sclerosis can cause blindness and paralysis as well as recurring and unexpected seizures. MS sufferers are given highly toxic drugs that can help alleviate their seizures but in and of themselves may carry life-threatening side effects. Lemtrada lawyer handling claims nationwide offer a free consultation and no obligation to file a claim.

Individuals that suffer from Multiple Sclerosis (MS) have a right to be concerned and to question the safety of the anti-seizure drugs they are given. This has never been truer than now that the US Food and Drug Administration (FDA) has identified the popular MS drug Lemtrada as being linked to causing strokes and sudden death in some patients. The National Multiple Sclerosis Society has acknowledged the FDA's concerns and published a piece to further alert MS patient taking Lemtrada.

Lemtrada was approved for sale in 2014 and since then 13 cases of stroke have been reported to the FDA by those taking the drug. Patients report that shortly after receiving an infusion of Lemtrada (alemtuzumab, Sanofi Genzyme), experiencing "serious cases of stroke and tears to the wall of arteries in the head and neck." According to the NMSS, these problems can lead to serious disability and death. Lemtrada's boxed warning has been updated to reflect the newly-established danger however it is unlikely that a patient will ever see the new warning. MS patients are reliant on their physician to not only notice the new warning label but also to inform their patients and risk being second-guessed as to their professional judgment. Physicians are more likely to remain vigilant and closely watch their MS patients immediately during and after a Lemtrada infusion for signs of "sudden numbness or weakness in the face, arms, or legs, especially if it occurs on only one side of the body, sudden confusion, trouble speaking, or difficulty understanding speech, sudden trouble seeing in one or both eyes, sudden trouble with walking, dizziness, or loss of balance or coordination, and sudden severe headache or neck pain," according to the NMSS and the FDA.

Lemtrada causes tears to the wall of arteries in the head and neck, creating a condition called ischemic and hemorrhagic stroke and cervicocephalic arterial dissection. Ischemia is defined in Wikipedia as "a restriction in blood supply to tissues, causing a shortage of oxygen that is needed to keep tissue alive. Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue. Cervicocephalic syndrome (CCS) includes "pain and stiffness of the upper cervical spine with an associated headache.." Generally speaking, Lemtrada causes the walls of the arteries leading to the brain to become weakened and tear resulting in less oxygen-rich blood getting to the brain. The first sign of a The early warning signs of a Lemtrada stroke such as a severe headache that rapidly leads to unconsciousness and then brain damage are easily misdiagnosed until it is too late to prevent a stroke.

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